Monday, April 30, 2007

Personalized Medicine in Hepatitis

From Stanford today a study results released showing the effectiveness of a genetic test indicating which patients infected with the Hepatitis C virus will progress to cirrhosis (destroyed shrunken liver). Until this study gastroenterologists had to guess which patients would develop this condition. None of the clinical factors including alcohol use or age at infection could accurately predict cirrhosis. This signature panel of 7 single nucleotide polymorphisms predicted risk better than clinical factors. Does that mean this test co developed by Celera Genomics is useful for all? Well....

  1. We need validation studies
  2. This was just evaluated on Caucasians
  3. We are getting closer
  4. Now if we could just get one of these for hepatocellular cancer

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