Wednesday, April 11, 2007

Genes predict metastases

Today in the Journal Nature it is reported that there is a panel of four genes that when expressed enable breast cancer cells to metastasize to the lungs. Those genes EREG, MMP1, MMP2 and Cox2 when shut off have dramatic effect. These results make us question the utility of pulling drug like Vioxx (a COX2 inhibitor) off the market. Perhaps we can find a way to give this drug to those who need it and will not have adverse drug reactions. I am betting Vioxx will see the light of day again.
What do you think?

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