Wednesday, February 2, 2011

Coriell and OSU integrate GWAS into an EMR!

Ok, so enough with the acronyms.....

I am back and will be blogging more often again. So for those who still lurked around, tell the others that the Howard Stern of Genomics is back. I took a social networking holiday for a solid 2 months, plus the addition of having my practice change quite a bit after my USA Today and follow ups in the local papers.....

Today I want to announce that Coriell Personalized Medicine Collaborative and Ohio State University will be using data from an arm of the CPMC and OSU to integrate genetic risk data into the medical record.

Correct me if I am wrong, but I don't know of anyone else doing this exact same thing.

Ideally they will also continue to roll things in like PGx data. (I know this data will be coming soon)

By integrating things like Plavix response, you can make more gametime decisions easily.
I.E. Patient presents to the ED with a heart attack. Armed with prior knowledge about plavix nonresponder, you pick Effient.

What is so awesome about this arm is that Primary Care Physicians, Cardiologists AND patients will be participating and receiving results.....

They will be studying the behavior and knowledge of participants in the study, we have seen other data on this sort of thing, I wonder if we will see the same thing here.

For risk data? Probably. For PGx Data? Probably not.

Why? A plavix response in the medical record is a game changer.
3 Reasons

1. The clinician will be hit in the face with a "Plavix doesn't work here"
2. The physician may even find they are a nonresponder
3. There has got to be some hustling attorney out there, who will be lurking once they see the CPMC/OSU release. I am certain at least the physicians will be thinking so.....

The Sherpa Says: Study of clinical use and behaviors will be key to know how vital this data is and thus how tightly we should regulate its use in medical records i.e. 23andMe clinical BRCA testing! P.S. Like our new crest?


Chris said...

Hi. I just found your blog. Hope you post some on the recent FDA hearings, etc.

Anonymous said...

Hi Steve, like the blog. Just curious how you see the whole Plavix PGx thing shaking out in the near term. The CYP2C19 data seems like it might not be as strong as it first appeared, and the PON1 data are compelling. It's a bit muddy still to make clinical calls based on genotype re: plavix response, no?

Medical Supply said...

What is so awesome about this arm is that Primary Care Physicians, Cardiologists AND patients will be participating and receiving results i am very inspired from Coriell and OS U integrate GWAS into an EMR!
Thanks for sharing..

applepea said...

Looks like this Fox Chase/OSU connection is dynamic....good luck...I have been impressed by OSU's CTSA.
apparently UCONN is about to embark on their "personalized genomic Medicine" project with Jackson Labs (via Singapore genetics Institute)....the governor considers New Haven, Farmington and Storrs to be a research triangle!!!

will be very interested to learn about how OSU does integrate Genetic info into a Patient's EMR.
Learned about Helix and Corriel via Fox chase website.

I am a subscriber to 23andMe for about a year and for the $5/mo, find that-- useful, general information comes my I can tell my doc that I am an excess coumadin risk, if needed...however, the problem I see is that my 23andMe, 4star info cannot x reference any data
(except via me, an MD with 30 yrs experience and Pathology boards) mined records on me from all the dispersed locations where they exist.