I never realized

How a little blogpost can get investors excited. Since the Scienceroll and Now GTO posting I have been fielding a significant amount of calls regarding potential partners in Helix Health of Connecticut.

I have to admit, I am honored. But I also have to admit, I am surprised that these highly intelligent people never thought to call me before. I even do some consulting work for these groups, yet none asked about Helix Health of Connecticut.

Well, enough about me. What about personalized medicine? In case you missed it, Sequenom has been pushing the envelope lately. This new technology discussed here may remove the need for amnios....forever!

What is going on in November? Starting today, Burrill and Company has been discussing Personalized Medicine. I would love to hear from anyone who went to this conference! I am really sad that I missed this. I was planning on attending, but family came first :)

Harvard Partners Centers for Genetics and Genomics is hosting yet another conference "A Call to Action" is going to be held on November 29th. Lawrence Lesko, Mike Leavitt and Ralph Snyderman will be speaking. These are three speakers who have heard and loved. If you haven't this conference is a must!

This article from the Minnesota Star Tribune raises some questions and reminds us that not all support personalized medicine. We do have detractors. This is why we must not become a mutual admiration society. There is much work to be done to convince the public AND the health care field!

The Sherpa Says: Perceived competition is misperception. I think Berci has already pointed this out. We need to form partnerships to pilot this ship!

Archon X-Prize Here We Come

This week in the Proceedings of the National Academy of Science an article entitled:
"Single-molecule mass spectrometry in solution using a solitary nanopore" was published.

Why is this mouthful of words important? Well, the future of genetic testing and sequencing is going to change and this is the likely direction. This pore, created by a bacteria (Staph Aureus) is only 1.5 nanometers. For appreciation, the human hair is 10,000 nanometers. What I think is ironic is that the enzyme used to create the pore actually gives staph its ability to really make us humans sick. The technique used is remarkable...I don't know if anyone has seen a tandem mass spec before. But it usually takes up the size of a lab table. This procedure could actually be accomplished on a microchip!!! This study is a proof of concept study done in Ohio and Brazil which demonstrates the fidelity of molecule size prediction. I am sure there will be more to follow.

In addition Harvard has gotten into the game of nanopore sequencing and will likely be the world leader. But this is no surpirse. They have been in this nanopore game since the early 2000s (did I just say that?) The rough estimate for launch in this project has just gone from 7 years to 3.

The biggest problem clinicians have with genetic testing is it often takes too long with some of the quickest results taking longer than 6 hours. Nanopore sequencing could give answers in less than 2 hours. This would allow a physician to dose medicines, change treatments, identify disease in a much more reasonable window of time.

Do I see nanopore sequencing being used in the ED? Not quite yet, but the pharmacogenomic implications for personalized medicine are huge!!!!

Thanks Jason for putting this on the Radar Screen back in March.